"Functional biomarkers in psychiatry and neurology"

Quantitative EEG, event related potentials and neurotherapy.

 

Workshop

In Cambridge, England

With

Jury D. Kropotov

 
 

Saturday 8th to Tuesday 11th of April 2017

The cost of the 4 days will be: £600
(or £150 a day)

 

 

Prof. Jury Kropotov New book

Functional neuromarkers for psychiatry

Kropotov Juri D.

Mental illness represents the biggest challenge for modern health care systems. Recent advances in neuroscience have allowed scientists to explore functional neuromarkers of psychiatric disorders. The decades of brain and brain discovery (1990-2010) are followed by the decade of translation that focuses on application of neuromarkers for providing an early detection, prevention, as well as a personalized care for patients with mental problems. The main goal of the book is to introduce the neuroscience methodology into psychiatric practice.

 

The functional neuromarkers analyzed in the book include brain activation patterns revealed by functional magnetic resonance imaging (fMRI), positron emission tomography (PET), quantitative electro-encephalography (qEEG) and event-related potentials (ERPs). To be used in clinical practice an ideal neuromarker must have a diagnostic sensitivity and specificity higher that 80%, to be reliable, reproducible, and inexpensive to measure, non-invasive, and simple to perform, and confirmed by at least two independent studies. The functional neuromarkers for ADHD, schizophrenia and obsessive-compulsive disorder are reviewed in detail.

 

The book is based on the author's experience in search for functional neuromarkers in the healthy and diseased brain. The book focuses on recently emerged methods of analysis of EEG and ERPs with the goals of 1) elucidating neuronal mechanisms of generation of EEG spontaneous rhythms, and 2) determining functional meaning of ERP components in cognitive tasks. The mechanisms of neuromodulation methods such as Transcranial Magnetic Stimulation (TMS), Transcranial Direct Current Stimulation (tDCS), Deep Brain Stimulation (DBS) and neurofeedback are presented. A separate part of the book is dedicated to application of the whole methodology for 1) diagnosis, 2) personalized neurotherapy and 3) monitoring the results of treatment of ADHD, schizophrenia and obsessive-compulsive disorder.

The Workshop:

° The goal of the workshop is to teach attendees how to improve their diagnostic and treatment tools by using a newly emerged technology of Quantitative EEG, event related potentials and neurotherapy.
° The attendees are required to bring laptops with them. At the workshop the attendees will be supplied by an educational software and EEG files from the HBI (Human Brain Index) reference database.

° Each day will consist of two parts:
Morning: theoretical usually by lectures and practice with software on EEG files taken from the HBI reference database and

afternoon; working with hardware/software, recording EEG and analyzing EEG files recorded during the workshop.

° The attendees will be supplied with hardware for recording EEG. Each attendee will get the opportunity to record and analys EEG and ERP by themselves.

 

Professor Juri D. Kropotov book on the topic:
"Quantitative EEG, event related potentials and neurotherapy"



The courses will cover

First day

Second day

Third Day

Fourth day

 
 

First day

Morning
Topics:
° Generators of EEG rhythms.
° Background EEG as a reflection of cortical self regulation.
° What does clinical EEG mean?
° Pathological EEG patterns (slow waves, spikes, paroxysms….) in epilepsy, brain tumors, and some other brain disorders.
° Mapping potentials
° Generating Slow Resolution Electromagnetic Tomography (LORETA and s-LORETA) from the spectral maps.
 
The aim is teach attendees the foundations of clinical EEG, namely:
1) neuronal basics of brain rhythms
2) methods of recording and montaging,
3) how to distinguish non-EEG artifacts from EEG records,
4) to correct artifacts using available software,
5) to distinguish pathological EEG patterns by means of visual inspection as well as by means of automated tools.
6) to use brain maps and s-LORETA imaging for depicting the data.
Procedure: lecture (power point presentation is supplied), practice with EEG records on healthy subjects and patients from the HBI database (software and EEG files are supplied).
 
Afternoon
Topics:
° recording EEG in resting state (eyes open, eyes closed, hyperventilation)
° visual inspection of the EEG recording
° artifact correction
° automated spike detection.
 
the aim is to teach attendees:
1) to place electrodes on the patients head according to 10-20 system,
2) to start, end and store an EEG recording,
3) to be able to use the built-in database to manage the datasets,
4) to remontage the recording.
Procedure: the attendees will be divided into groups. Each group will be supplied with hardware/software for recording and analysis. One of the attendees will serve as a subject (to be recorded) while the others will record.

Second day

Morning
Topic:
° quantitative EEG as a method for neuro-metrics
° qEEG-endophenotypes (biological markers) in the healthy population
° qEEG-endophenotypes in brain disorders
 

The aim is to teach attendees methods of spectral analysis, including
1) Fourier and wavelet transformations,
2) coherence,
3) event related de-synchronization, as well as to show how these methods enable us to reveal
4) QEEG-endophenotypes of brain disorders such as ADHD, dyslexia, anxiety.

Procedure: lecture, practicing with EEG records on healthy subjects and patients from the HBI database.
 
Afternoon
Topic:
° Spectral and coherence analysis of EEG recorded on the first day
° Comparing spectral characteristics of recorded EEG with the normative data of the HBI reference database.
 
the aim is to teach attendees:
1) to remontage the recording into the HBI database montage,
2) to perform spectral and coherence analysis,
3) to compare the results of the analysis with the HBI database,
4) to interpret the results.
 
Procedure: the attendees will be divided into groups. Each group will be supplied with software for analysis of the EEG of the group. Spectra, coherence, theta/beta ratios, asymmetry maps for EEGs recorded in the first day will be computed and analyzed.

Third Day

Morning
Topics:
° Event related potentials (ERPs) as markers of stages of information flow in the brain.
° Association of ERP components with functioning of brain systems.
° Reflection of dysfunctioning of brain systems in ERPs components.

The aim is to teach attendees methods of Event Related Potentials, including
1) averaging technique,
2) Independent Component Analysis (ICA),
3) to show the discriminative power of ERPs in ADHD, dyslexia and traumatic brain injury etc.

Procedure: lecture, practicing with EEG records on healthy subjects and patients from the HBI database.
 
Afternoon
Topic:
° Recording of EEG in a Visual Contingent Performance Task (VCPT).
° Preprocessing EEG
° Computing ERPs by averaging techniques
° Comparison behavioral of parameters (omission and commission errors, latencies and variances of responses) with the normative data of the HBI database
° Comparison of ERPs with the HBI database
° Comparison of ICA components of ERPs with the normative data.
 
The aim is to teach attendees:
1) to use Psytask software for presenting tasks provided with the HBI database,
2) to record EEG in one of the tasks (such as VCPT),
3) to compute ERPs and behavioral parameters,
4) to analyze ERPs visually and to make maps was well as LORETA images of ERPs components,
5) to compare ERPs and ERP components with the HBI reference database.
 
Procedure: the attendees will be divided into groups. Each group will be supplied with hardware/software for recording and analysis. One of the attendees will serve as a subject (to be recorded) while the others will do recording. EEG in the VCPT task will be recorded and analyzed.

Fourth day

Morning
Topics:
° Neurofeedback and tDCS as tools of neurotherapy
° Neurotherapy for peak performance in healthy subjects
° Neurotherapy for correcting cortical dysregulation in brain disorders
° Neurotherapy for correcting disorders of information flow.
 
The aim is to teach attendees methods of neurotherapy, including
1) QEEG-based neurofeedback,
2) s-LORETA neurofeedback,
3) ICA-neurofeedback,
4) ERP-based neurofeedback,
5) transcranial Direct Current Stimulation,
6) Transcranial Magnetic Stimulation (TMS).
 
Procedure: lectures, practicing with EEG records on patients from the HBI database and constructing neurotherapy protocols.
 
Afternoon
Topics:
° Analysis of EEG records made during the first days.
° Constructing neurotherapy protocols for peak performance by using the recorded EEG files.
° Analysis of EEG records of patients from the HBI reference database.
° Constructing neurotherapy protocols for treatment.
 
The aim is to teach attendees to use the HBI reference databse for construction of protocols for neurotherapy.
 
Procedure: attendees will be divided into groups. Each group will be supplied with an HBI database. The records made during the first days will be analyzed and neurofeedback protocols for peak performance will be suggested. Several records from patients of the HBI database will be analyzed.

 

qEEG Course Location:

The Open University in Cambridge
In The East Of England
Cintra House,
12 Hills Rd,
Cambridge, CB2 1PF

Tony Steffert
07966 484 289
Getting to the Open University:

By Train:

Cambridge is on the main line train route from both London King's Cross and Liverpool Street stations. Non-stop trains take 45 minutes.
National Rail Cambridge

The train station is a 10 min walk to the OU campus.

There is a taxi ranks at the train station.

 

By Bus:

The stop is called St Paul's Road and is very near the OU campus.

The Buses: 1A, 3, and 13, 13A, 13B, 13C

The Bus 1A and 3, go to and from the Train station to the City centre and the OU is in the middle.

 

By Coach:

Drummer Street Bus Station
Cambridge, CB1 1NQ

The coach station is an simple 12 min walk to the OU Campus or Bus 3.

 

By Car:

Traffic can be surprisingly bad for such a small town!


There is no parking available at the OU regional centre.

 

There are two car parks near by:


Queen Anne Terrace Car Park
Gonville Place, (A503)
Cambridge CB1 1ND
(570 spaces, 21 Blue Badge (disabled parking) bays)

Near the swimming pool on Parker's Piece. This is a 6 min walk to the OU.

Monday to Sunday, 24 hours, Over 6 hours £13.30.


There is an NCP Car Park at the Train Station.
(372 spaces, 7 Disabled bays)

NCP Parking

Pay on the day: £10.00 (I think)

This is a 10 min walk to the OU.


Park & Ride

There are 5 Park & Ride

The Babraham Road Park & Ride bus stop at Emmanuel St (E5) which is a 10 min Walk.
Info.

The Trumpington Park & Ride just off the M11 stop at Downing St near John Lewis a 8 min walk to OU. It will also stop at the Botanic Garden 8 min walk.
Info.

Parking seems to be £4 a day. (£3 for the bus and £1 for the parking)
(But the website is not that clear, so if you are thinking of using the Park & Ride, just email me and I can find out more, tony@qeeg.ck.uk)


 

 

 

Accommodation:

 
You are advised to book your accommodation early, as Cambridge in the Summer is a busy tourist destination.
 
The following websites may be useful:
 
•For Hotels and Bed and Breakfast: http://www.visitcambridge.org/
•For single rooms or small group apartments: https://www.airbnb.co.uk
•For rooms in Cambridge colleges: https://www.meet-cambridge.com/how-we-can-help/stay-in-a-cambridge-college

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8th Saturday April 2017
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To Make a Payment, please fill in the online Booking form and make a Bank transfer to one of the three accounts:

English Sterling Euro account US Dollar account
 
Or to pay by Cheque please fill in the online Booking form and send your Cheque See below:
 

To pay by Credit Card, fill in the online Booking form for the course

Then just email me



and I will send you a 'PayPal' Payment request. (You do NOT need a 'PayPal' account) It is very easy to do.


 
 
This is our English Sterling Bank account
 
Name of Account: Learning Recovery
 
IBAN: GB24 CPBK 08929969563229
BIC/Swift: CPBKGB22
 
Sort: 08-92-99
Acc: 69563229
 
The Co-operative Bank
PO Box: 250
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WN8 6WT

 

 

This is our Euro Bank account

 

Name of Account: Tony Steffert
 
IBAN: DE59 6605 0101 1020 8562 07
BIC/Swift: KARSDE66
 
Acc/Kontonnummer: 1020856207
 
Sort Code/Bankleitzahl: 660 501 01
 
Sparkasse Karlsruhe Ettlingen
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76133 Karlsruhe
DE143588630

 

 
This is our US Dollar Bank account
 
Name of Account: Beverley Steffert
 
16-49 82
Acc No.: 0821221512
 
Routing: 122000496
Swift Code: BOFCUS33MPK
 
Union Bank of California
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Suite 100
San Diego,
CA
92103

 

To pay by Cheque please fill in the online form and send your Cheque to:
 
Cheque made payable to:
Learning Recovery
 
send your Cheque to:
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London
NW6 7BB
U.K.
 
 
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